Exemestane Vision Changes: What You Need to Know

When you’re taking Exemestane, a type of aromatase inhibitor used to treat hormone-receptor-positive breast cancer in postmenopausal women. Also known as Aromasin, it works by lowering estrogen levels to slow cancer growth. But like many hormonal treatments, it doesn’t just affect cancer cells—it can ripple through your whole body, including your eyes. Vision changes aren’t the most common side effect, but they’re reported often enough that ignoring them isn’t an option.

People on Exemestane, a type of aromatase inhibitor used to treat hormone-receptor-positive breast cancer in postmenopausal women. Also known as Aromasin, it works by lowering estrogen levels to slow cancer growth. But like many hormonal treatments, it doesn’t just affect cancer cells—it can ripple through your whole body, including your eyes. have described blurry vision, difficulty focusing, or seeing floaters. These aren’t always serious, but they can be early signs of something bigger. Estrogen plays a role in maintaining the fluid balance and blood vessel health in your eyes. When Exemestane cuts estrogen sharply, it can lead to dry eyes, increased eye pressure, or even rare cases of retinal changes. The FDA has flagged visual disturbances as a possible adverse reaction, and several case reports link long-term use to temporary or persistent vision issues.

It’s not just about the drug itself—your age, other medications, and pre-existing conditions like diabetes or high blood pressure can make vision problems more likely. If you’re also taking steroids, antihypertensives, or even over-the-counter antihistamines, those can stack up and worsen eye dryness or pressure. That’s why tracking changes matters. A simple test: if your vision feels off for more than a few days, or if you see flashes, shadows, or sudden blurring, don’t wait. Talk to your oncologist and get an eye exam. Most eye issues from Exemestane are reversible if caught early, but ignoring them can lead to lasting damage.

You’re not alone in noticing this. Many women on hormonal therapies report similar symptoms, but few bring them up unless asked. Doctors focus on cancer control, and vision changes often get pushed to the side. But your eyes matter too. The posts below cover real cases, comparisons with other aromatase inhibitors like letrozole and anastrozole, how to spot early warning signs, and what steps you can take—whether it’s switching meds, using lubricating drops, or adjusting your routine—to protect your vision while staying on treatment.