Propranolol: What It Does and How to Use It Safely
Propranolol is an old but powerful beta blocker first used in the 1960s. It slows the heart, lowers blood pressure, and can reduce tremors and anxiety. That makes it useful for conditions from high blood pressure to performance anxiety — but it can also cause serious problems if used the wrong way. Here’s what you need to know in plain language.
Common uses and typical dosing
Doctors prescribe propranolol for several things: high blood pressure, angina (chest pain), some arrhythmias, migraine prevention, essential tremor, and short-term performance anxiety (stage fright). Typical dose ranges are:
- Hypertension/angina: often 40–160 mg per day in divided doses.
- Migraine prevention: commonly 80–240 mg per day (split doses or extended-release).
- Performance anxiety: a single 10–40 mg dose usually 30–60 minutes before an event.
- Tremor: 40–120 mg per day depending on response.
These numbers are general. Your doctor will pick the right dose based on your health, other meds, and how you respond.
Side effects, interactions, and who should avoid it
Common side effects include tiredness, cold hands/feet, dizziness, and sleep changes. More serious risks are slow heart rate (bradycardia), low blood pressure, and breathing trouble — especially in people with asthma or COPD. Stopping propranolol suddenly can cause a rebound fast heart rate or angina, so taper under medical guidance.
Propranolol interacts with other medicines that lower heart rate or blood pressure (calcium channel blockers, digoxin), some antidepressants, and drugs that affect liver enzymes. It can mask low blood sugar signs in diabetics, so check blood glucose more often if you’re diabetic. Also be cautious with alcohol and sedatives because they can increase dizziness.
Don’t take propranolol if you have uncontrolled asthma, severe bradycardia, or certain types of heart block unless your doctor says it’s OK. Pregnant or breastfeeding? Talk to your clinician — sometimes it’s used, but risks and benefits must be weighed.
Practical tips: take regular-release versions two to three times daily or use extended-release once daily. You can take it with or without food, but taking it the same way each day reduces stomach upset. Measure your pulse and blood pressure at home for the first few weeks. If you get shortness of breath, severe dizziness, or fainting, seek care fast.
Buying and prescriptions: propranolol is prescription-only in most places. Avoid sketchy online pharmacies — look for a valid prescription and clear contact info. Our site covers how to spot legit online pharmacies and what safety checks to run before ordering medication.
Questions for your prescriber: ask why propranolol is best for your condition, how long you’ll need it, what exact dose to start with, and what to do if you miss a dose. Clear answers will make using propranolol safer and more effective.

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