Bruising: Causes, Medications That Cause It, and What to Do

When you notice bruising, a discoloration of the skin caused by broken blood vessels under the surface. Also known as ecchymosis, it’s often harmless—but when it happens too easily or without reason, it can signal something deeper. Most people get a bruise now and then from bumping into something. But if you’re seeing purple or yellow marks appear with little to no trauma, you’re not alone. Many people on common medications report unexplained bruising, and it’s not always just aging skin.

Blood thinners, medications that reduce your blood’s ability to clot. Also known as anticoagulants, they’re prescribed for heart conditions, atrial fibrillation, and after surgeries. Drugs like warfarin, aspirin, and even over-the-counter NSAIDs can make bruising more likely. Then there’s Orlistat, a fat-blocking weight loss pill. Also known as Alli or Slim Trim Active, it’s not directly linked to bruising—but it can interfere with vitamin K absorption, which your body needs to form clots. That’s one less-known connection. Other culprits include steroids, antidepressants, and certain antibiotics like fluoroquinolones, which can weaken blood vessel walls. Even supplements like fish oil, ginkgo, or high-dose vitamin E can thin your blood enough to cause easy bruising.

It’s not just drugs. Low platelet counts, liver disease, leukemia, and autoimmune disorders like ITP can also lead to unexplained bruising. Older adults often bruise more because their skin gets thinner and blood vessels more fragile. But if you’re young, healthy, and suddenly bruising like you’re in a fight every week, that’s a red flag. Keep track of where the bruises show up, how often, and if you have other symptoms like nosebleeds, bleeding gums, or unusual fatigue. These aren’t just cosmetic issues—they’re clues.

The posts below dig into exactly this. You’ll find real-world examples of how medications like Exemestane, Hydroxyzine, and Ofloxacin affect your body in ways you might not expect—some linked to skin changes, bleeding risks, or immune responses that show up as bruising. Others explain how to track FDA safety alerts that update drug warnings, so you know when a medication you’re taking might start causing new side effects. Whether you’re trying to figure out why you’re bruising more than usual or just want to understand how your pills might be affecting you, these guides give you the facts without the fluff.